To all of our great customers: You may have noticed that some of our prices are much higher than normal. This is because Life Extension is enforcing a MAP - Minimum Advertised Price. This is the price we have to advertise, but we can sell for less. We can and will still sell to you at the low prices you have come to expect! Just use the "make offer" button and enter the price that you normally pay! If you don't know the price, just message and we will let you know. Thank you - we appreciate your business! TWO BOTTLES FRESH PRODUCT! SHIPS TO YOU STRAIGHT FROM LIFE EXTENSION! BUY IT NOW AND SAVE! Super Carnosine Antioxidant Anti-Glycation Agent 500 mg, 60 vegetarian capsules Carnosine is a multifunctional dipeptide made up of the amino acids beta-alanine and L-histidine.1It is found both in food and in the human body. Long-lived cells such as nerve cells (neurons) and muscle cells (myocytes) contain high levels of carnosine.1 Muscle levels of carnosine correlate with the maximum life spans of animals. Carnosine has a number of antioxidant properties and has been shown to be an anti-glycating agent.2-8 This nutrient has the ability to suppress formation of advanced glycation end products (AGEs) and inhibit the formation of reactive oxygen species (ROS),9-12 a culprit in oxidative stress that can lead to age-related conditions.13-15 Carnosine levels decline with age. Muscle levels decline 63% from age 10 to age 70, which may account for the normal age-related decline in muscle mass and function.16 Since carnosine acts as a pH buffer, it can keep on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart myocytes.17 Aging causes damage to the body?s proteins. One underlying mechanism behind this damage is glycation. Glycation involves the non-enzyme controlled cross-linking of proteins or lipids and sugars to form non-functioning structures in the body. The process of glycation can be superficially seen as wrinkled skin. Glycation is also an underlying cause of age-related neurologic, vascular, and eye problems.18-29 Carnosine is a unique dipeptide that can interfere with the glycation process.2-8 Benfotiamine, a derivative of thiamine (vitamin B1), provides additional protection against glycation reactions. Even people with normal glucose levels encounter damaging sugar reactions over a lifetime. Benfotiamine protects against glucose-induced cell damage via several mechanisms.30-36 Supplement Facts Serving Size 1 vegetarian capsule Amount Per Serving Thiamine (vitamin B1) (as thiamine HCl) 50 mg L-Carnosine 500 mg Benfotiamine 50 mg Luteolin [from orange extract (fruit)] 4 mg Other ingredients: vegetable cellulose (capsule), rice flour, ascorbyl palmitate, silica, hydroxypropyl methylcellulose. Non-GMO Dosage and Use Take one (1) capsule two to three times daily with or without food, or as recommended by a healthcare practitioner. RETURN POLICY: If you are not 100% satisfied with your purchase, please contact us IMMEDIATELY and we will make it right! We can only accept UNOPENED bottles for return or exchange. ATTENTION: PLEASE BE ADVISED THAT LIFE EXTENSION HAS A NEW LOOK! AS THEY PHASE OUT THE BOTTLES YOU ARE USED TO, YOU WILL START RECEIVING THE NEW BLUE BOTTLES! ATTENTION: LIFE EXTENSION MAY TAKE LONGER TO SHIP DUE TO AN INCREASE IN ORDERS BECAUSE OF THE CURRENT SITUATION. YOUR ORDER MAY ARRIVE LATER THAN USUAL. THANK YOU FOR YOUR PATIENCE! WE APPRECIATE YOUR BUSINESS!