FOUR BOTTLES BUY IT NOW AND SAVE! FRESH PRODUCT! SHIPS TO YOU STRAIGHT FROM LIFE EXTENSION! Mega Benfotiamine 250 mg, 120 vegetarian capsules Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress. For example, the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes, transketolase requires a co-factor. In this case, it needs assistance from thiamine. Unfortunately, thiamine is water-soluble, which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine. In a landmark study, benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%, compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage. Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB), which is implicated in numerous inflammatory conditions. Overall, benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. Benfotiamine also helps maintain healthy endothelial function and supports the health of the nerves, kidneys, eyes, blood vessels, and heart. Supplement Facts Serving Size 1 vegetarian capsule Amount Per Serving Thiamine (vitamin B1) (as thiamine HCl) 10 mg Benfotiamine 250 mg Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), dicalcium phosphate, rice flour, vegetable stearate, silica. Non-GMO Dosage and Use Take one (1) to four (4) capsule(s) daily with or without food, or as recommended by a healthcare practitioner. RETURN POLICY: If you are not 100% satisfied with your purchase, please contact us IMMEDIATELY and we will make it right! We can only accept UNOPENED bottles for return or exchange. PLEASE SEE OUR RETURN POLICY UNDER THE SHIPPING AND PAYMENTS TAB! THANK YOU! ATTENTION: PLEASE BE ADVISED THAT LIFE EXTENSION HAS A NEW LOOK! AS THEY PHASE OUT THE BOTTLES YOU ARE USED TO, YOU WILL START RECEIVING THE NEW BLUE BOTTLES! ATTENTION: LIFE EXTENSION MAY TAKE LONGER TO SHIP DUE TO AN INCREASE IN ORDERS BECAUSE OF THE CURRENT SITUATION. YOUR ORDER MAY ARRIVE LATER THAN USUAL. THANK YOU FOR YOUR PATIENCE! WE APPRECIATE YOUR BUSINESS!