In Mexico the plant is used as an herbal remedy for dysentry and fever. The Zoque Popoluca people call the plant tam huñi ("bitter gum") and use it to treat diarrhea and asthma, and the Mixe people know it as poop taam ujts ("white bitter herb") and use it for stomachache and fever.[4]
The Chontal people of Oaxaca reportedly use the plant, known locally as thle-pela-kano, during divination. Isolated reports describe rituals that involve smoking a plant believed to be this species, drinking it as a tea, and placing it under a pillow to induce divinatory dreams. Zacatechichi, the former species name, is a Nahuatl word meaning "bitter grass". Users take the plant to help them remember their dreams; side effects include nausea, and vomiting.