Esoxx One is a combination of hyaluronic acid and chondroitin sulfate, which protect the esophageal mucosa due to their original and innovative mechanism of action. The product also contains poloxamer 407, an ingredient with high adhesion to the esophageal mucosa. Thanks to it, hyaluronic acid and chondroitin sulfate coat the mucosa longer, protecting it from the effects of hydrochloric acid produced in the stomach. Gastroesophageal reflux disease is characterized by symptoms such as heartburn, accumulation of gastric contents into the esophagus, irritative cough, and dysphonia, which may or may not be associated with the presence of inflammatory erosive lesions of the esophageal mucosa.