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Lactuca serriola, also called prickly lettuce, milk thistle (not to be confused with Silybum marianum, also called milk thistle), compass plant, and scarole, is an annual or biennial plant in the tribe Cichorieae within the family Asteraceae. It is the closest wild relative of cultivated lettuce (Lactuca sativa L.).  Lactuca serriola is known as the compass plant because in the sun the upper leaves twist round to hold their margins upright.

Culinary and medicinal uses
Lactuca serriola can be eaten as a salad, although it has something of a bitter taste. Young leaves can be eaten raw or cooked. Older leaves can be steamed. While unsubstantial, its roots have been used as a coffee substitute.

Its presence in some ancient deposits has been linked more to its soporific properties which might suggest ritual use. The Ancient Greeks also believed its pungent juice to be a remedy against eye ulcers and Pythagoreans called the lettuce eunuch because it caused urination and relaxed sexual desire. Following its accidental introduction to North America, the Navajo began to use the plant as a ceremonial emetic. In the island of Crete in Greece the leaves and the tender shoots of a variety called maroula (μαρούλα) or agriomaroulo (αγριομάρουλο) are eaten boiled. It is used by a growing number of Jews and Samaritans as the Maror (bitter herb).

Lactuca serriola contains lactucarium, which is the milky sap (white latex) that flows through the stem of the plant. It is used as a medicinal herb when dried after contact with air. Although the standard definition of lactucarium requires its production from Lactuca virosa, it was recognized that smaller quantities of lactucarium could be produced in a similar way from Lactuca sativa and Lactuca canadensis var. elongata, and even that lettuce-opium obtained from Lactuca serriola or Lactuca quercina was of superior quality

Lactuca serriola can be eaten as a salad, although it has something of a bitter taste. Young leaves can be eaten raw or cooked. Older leaves can be steamed. While unsubstantial, its roots have been used as a coffee substitute.