Published Apr 2001 by Wildstorm
Written by Kris Oprisko and Ted Adams
Art by Shawn Crystal and John Nyberg
Cover by Lee Bermejo
Full color, 32 pages

The secretive Umbrella organization reveals its plans for the X-Virus -- and how the captured members of the S.T.A.R.S. Charlie Team tie into those plans. Hint: Our heroes aren't going to be happy! The non-stop action unfolds in Mexico and Alaska, as Charlie Team battles zombies in both places!

Characters
Raquel Fields
Jesse Alcorn
Falcon
Quan Williamson
Rosa Cardenas
Patrick Brady
Mr. Venk
Klaus
Dr. Dexter Whitlam

At the Mexican temple, Falcon orders his two subordinates to remain quiet. Walking to the temple door, the three stumble into quicksand (behaving completely unlike genuine quicksand) and begin to sink. Raquel shoots at a cactus with her crossbow to save the three. Jesse grabs hold of the rope to safety. Falcon is too far away, so Raquel throws her crossbow to him once she is safe. Once all three are safely on hard ground, darts are shot out from the cacti. The three run up the steps of the temple, but are unable to get inside without a code - Jesse estimates 1.2 million possible entries, taking days for his computer to break it. Raquel decides to destroy the machine with explosives, instead, allowing entry immediately. Falcon spots a Licker, warning Jesse. Too busy looking at Falcon, confused, he fails to see the creature approach him. Ordering Jesse to stay still, Raquel and Falcon take down the Licker.

Moving on, Falcon deduces that Umbrella is using trained Lickers as guards as a replacement to humans. He also deduces that a newly engineered mutagenic virus may be responsible. Raquel moves through the vents to spy on the Umbrella researchers, finding that their initial location is too hard to hear. On a security camera, Rosa and Patrick are recognisable, revealing that the Mexican site is in contact with the Arctic Research Facility.

Meanwhile, at the facility, Rosa and Patrick wake up tied up, deducing that they have been taken captive. A senior researcher decides to explain. His explanation is not given to the reader, as the comic now moves to Quan, riding down in his snowmobile to the planned camp site. Finding the snowmobiles deserted and the weapons abandoned, he becomes concerned. He finds a small transmitter left by Patrick lying in the snow, allowing him to listen in on the researcher's conversation.

The researcher - Dr. Whitlam - explains that the t-Virus was powerful, but rendered the mental capacities of the infected, null. The G-Virus caused massive-scale mutations in its victims. Dr. Whitlam introduces to the two his newest development - the X-Virus. Klaus advises the doctor that it is not a good idea to divulge classified information to S.T.A.R.S. operatives, but he berates Klaus for questioning him - after all, Whitlam is in charge, now. He goes back to explaining the virus. "X" augments the fighting ability of the infected; not simply making them stronger and fiercer. Rosa comments that the infected they fought against were easy to kill; he responds that those were infected with the G-Virus; not "X". The purpose of the creatures encountered by Rosa and Patrick was to become worthy opponents of the X-infected Umbrella teams. He decided that Umbrella security teams should be augmented because they were absolutely hopeless in dealing with G-creatures. Which brings up the real reason Rosa and Patrick were kept alive - he is impressed by their fighting ability, and wishes to augment them into powerful B.O.W.s.

Back in Mexico, Raquel returns to Falcon and Jesse and reveals what she understands is going on in Alaska. They must finish the job here and move to Alaska. The three put on gas masks. Falcon shoots through a glass window looking into the laboratory, allowing Raquel to throw a gas grenade into the room to knock out any researchers and any Lickers inside. Jesse is ordered to move in and collect data from the computer terminals. As the other two move in, they discover a giant Tyrant in the room. The creature knocks out Raquel from behind, leading to a somewhat-emotional wave of fire from Falcon. Charging at him next, a bullet to the head finally takes it out moments before slashing at him, too. Jesse investigates the computer terminal and finds information on the X-Virus ("Just as I suspected"). He quickly moves through the information, which includes data on an antidote. The self-destruct is suddenly activated, forcing the three to run out of the temple/facility rather than search the site for the antidote, should it be there. Falcon berates Jesse for pressing the wrong button. Out of the fiery rubble that is the temple summit, the Tyrant walks out. Rosa takes a rocket launcher out of the team's parked vehicle and destroys the creature with a rocket.

Resident Evil, known in Japan as Biohazard,[a] is a Japanese horror video game series and media franchise created by Capcom. It consists of survival horror, third-person shooter, and first-person shooter games. The franchise has expanded into a live-action film series, animated films, television series, comic books, novels, audio dramas, and other media and merchandise.

In 2021, a reboot film was made, titled Resident Evil: Welcome to Raccoon City.

Despite all the installments receiving generally negative reviews from critics, the Resident Evil film series has grossed over $1.2 billion. At various points throughout the 2010s, the series was the highest-grossing film series based on a video game, the highest-grossing zombie film series, and the highest-grossing horror film series although it has since been surpassed in all of these categories.The series does hold the record for the most live-action film adaptations of a video game.

Constantin Film was in development of a Resident Evil animated series in 2005, intended as a spin-off of Resident Evil: Apocalypse which would continue Alice and Jill's adventures in the event Sony turned down work on a third film. When Resident Evil: Extinction was greenlit, this project was abandoned. A second attempt at a TV series arose in 2014; owing to a deterioration in Constantin's relationship with Sony Pictures over the cancellation of Mortal Instruments: City of Ashes and Sony Pictures Television's disinterest in the Shadowhunters series, Constantin began shopping around for alternate financiers with the intention it begin production following the release eof Resident Evil: The Final Chapter.

Work renewed on the television show project in late 2018 following the cancellation of Shadowhunters, with Constantin approaching Netflix to finance the film, with production outsourced to Moonlighting Film, their South Africa partner on The Final Chapter. The series was formally announced in 2020, having been greenlit as an eight episode series with each episode one hour in length. Andrew Dabb was hired as Showrunner alongside a number of other Netflix projects. Due to delays brought on by the pandemic, production was delayed eight months and took place from February-July 2021.

The story makes heavy use of flashbacks, set in both 2022 and 2036. The 2022 plotline involve 14-year-old half-twins Jade and Billie Wesker moving to New Raccoon City. They come to realize that their father may be concealing dark secrets, both that could destroy the world and reveal their true origins. The 2036 plotline takes place in a post-apocalyptic wasteland, where Umbrella's T-virus has spread across the world, mutating wildlife and six billion human victims, called "Zeroes", leaving behind a mere 15 million uninfected refugees. It follows Jade, now thirty, in her efforts to survive in this world. The series is scheduled to premiere on July 14, 2022.

A CG anime series, subtitled Infinite Darkness, starring Resident Evil 2 protagonists Leon S. Kennedy and Claire Redfield, was released on July 8, 2021 on Netflix.

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