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Biochemist Dr. Peter Blood, having been kicked out of Vienna for secretly testing his wild theories on human rather than animal subjects, returns home to Cornwall, where his doctor father, Robert Blood, is the General Practioner.

The lurid story is told from Peter's perspective, as he kidnaps local villagers, whisking them to a local abandonded tin mine in order to experiment on them, while at the same time trying to divert the criminal investigation. He pretends to cooperate with local policeman Sgt. Cook, and in an overused device, he bluffs his way through one tight spot after another by offering to do the very thing that would expose him. And each time Sgt. Cook declines what to him seems like an overly generous offer!

Peter's intentions are to employ curare, the poison famously used by South American natives, to paralyze humans for live organ transplants. According to Peter, the heart and other organs of a so-called worthless person (a homeless bum, for instance) could replace the weak heart of an esteemed scientist or great artist. The concept is certainly ghoulish:

A few shots of panicked but completely immobile victims watching helplessly as Peter operates on them (without anesthetic?) is squirmily unsettling, drawing also on the common fear of waking up during surgery. Late in the film, Peter revives a long-dead corpse and partly thanks to Sidney J. Furie's blood-and-thunder direction there's something of a payoff for the long wait.