O.J. Simpson signed limited edition litho. 24x28 inches Simpson attended the University of Southern California (USC), where he played football for the USC Trojans and won the Heisman Trophy in 1968. He played professionally as a running back in the National Football League (NFL) for 11 seasons, primarily with the Buffalo Bills from 1969 to 1977. He also played for the San Francisco 49ers from 1978 to 1979. In 1973, he became the first NFL player to rush for more than 2,000 yards in a season. He holds the record for the single season yards-per-game average, which stands at 143.1. He was the only player to ever rush for over 2,000 yards in the 14-game regular season NFL format. Simpson was inducted into the College Football Hall of Fame in 1983 and the Pro Football Hall of Fame in 1985. After retiring from football, he began new careers in acting and football broadcasting.