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Diosmin is a flavonoid most commonly found in citrus fruits. Flavonoids are plant compounds that have antioxidant properties, which protect your body from inflammation and unstable molecules called free radicals 

Diosmin was first isolated from the figwort plant (Scrophularia nodosa L.) in 1925 and has been used since 1969 as a natural therapy to treat various conditions, such as hemorrhoids, varicose veins, venous insufficiency, leg ulcers, and other circulatory issues.

It’s believed to help reduce inflammation and restore normal blood flow in people with venous insufficiency, a condition in which blood flow is impaired (2Trusted Source).

Diosmine has been widely used since 1969 as a phlebotonic and vascular protector for venous leg ulcers and hemorrhoids; however, clinical data to support these uses are limited. Most, but not all available clinical data support its use for chronic venous insufficiency (CVI) and hemorrhoid disease, both acute and chronic. Diosmin has also been used to improve postoperative cardiac function and outcomes in adults undergoing coronary artery bypass grafting (CABG) surgery, for pelvic congestion caused by pelvic varicose veins in men and women, and for varicoceles in men; however, few large-scale quality clinical trials support these uses.

Diosmin Similar to PHLEBODIA

Venotonic properties demonstrated in clinical pharmacology

- Increases the vasoconstrictor action of adrenaline, noradrenaline and serotonin on the superficial veins of the hand or on an isolated saphenous vein,

- Increase in venous tone, as evidenced by measurement of venous capacitance using strain gauge plethysmography; decrease in the volume of venous stasis,

- The venoconstrictive effect is dose-related,

- Lowering of mean venous pressure in both the superficial and deep systems, demonstrated in a double-blind, placebo-controlled Doppler trial.

Vasculoprotectiveproperties

- Increase in capillary resistance, dose-dependent effect

- Increase in systolic and diastolic blood pressure in postoperative orthostatic hypotension,

- Activity in the aftermath of saphenectomy.
Functional manifestations of veno-lymphatic insufficiency: heavy legs,
- Treatment of functional signs related to the hemorrhoidal crisis.

Oral use.

- In venous insufficiency: 1 tablet per day, in the morning before breakfast for 1 month.

- In haemorrhoidal crisis: 2 to 3 tablets per day at mealtime for 5 days.