Short description

Pharmacological action: Hepatoprotective, anti-inflammatory. Indications for use: Viral hepatitis (acute and chronic). Fatty liver degeneration (hepatosis). Other liver damage (medicinal, alcoholic, toxic). Liver cirrhosis. Intoxication. Psoriasis. Neurodermatitis inside. Eczema. adults and children over 12 years old, 1-2 capsules 3-4 times / day. with a meal, with a small amount of liquid.
pharmachologic effect

Combined drug. It has membrane stabilizing, hepatoprotective and antiviral effects. Phosphatidylcholine (the active substance of phospholipids) is the main structural element of cellular and intracellular membranes, is able to restore their structure and function in case of damage, providing a cytoprotective effect. It normalizes protein and lipid metabolism, prevents the loss of enzymes and other active substances by hepatocytes, restores the detoxifying function of the liver, inhibits the formation of connective tissue, reducing the risk of liver fibrosis and cirrhosis. Glycyrate (glycyrrhizic acid and salts) has an anti-inflammatory effect, inhibits the reproduction of viruses in the liver and other organs by stimulating the production of interferons, increasing phagocytosis, and increasing the activity of natural killer cells. It has a hepatoprotective effect due to antioxidant and membrane stabilizing activity. It potentiates the action of endogenous glucocorticosteroids, providing anti-inflammatory and anti-allergic effects in non-infectious liver damage. In case of skin lesions due to the membrane-stabilizing and anti-inflammatory action of the components, it limits the spread of the process and promotes regression of the disease.
Indications

- fatty liver degeneration (hepatosis); - other liver damage (alcoholic, toxic, including medicinal); - as part of the complex therapy of viral hepatitis, liver cirrhosis, and psoriasis.
Method of administration and dosage

The drug is taken orally with meals. The capsules should be swallowed without chewing with a small amount of liquid. Adults and children over 12 years of age are prescribed 2 caps. 3 times / day The duration of use can be up to 6 months, on average - 3 months.
Side effects

Usually the drug Phosphogliv® is well tolerated, side effects develop very rarely, according to post-registration observation, the frequency is <1/10 000. Allergic reactions: skin rash, difficulty in nasal breathing, conjunctivitis, cough. From the side of the cardiovascular system: transient (transient) increase in blood pressure, peripheral edema. From the digestive system: dyspepsia (belching, nausea, bloating), abdominal discomfort. If these symptoms occur, you should stop taking the drug and consult your doctor.
Contraindications

- antiphospholipid syndrome; - pregnancy (data on efficacy and safety are insufficient); - lactation period (data on efficacy and safety are insufficient); - children under 12 years old; - hypersensitivity to glycyrrhizic acid, phosphatidylcholine or other components of the drug. The drug should be prescribed with caution to patients with portal hypertension, arterial hypertension. If you have these diseases, you should consult your doctor before starting the drug.
Overdose

Currently, cases of overdose of the drug Phosphogliv® have not been registered.
special instructions

In case of an increase in blood pressure, you should stop taking the drug and consult a doctor. Influence on the ability to drive vehicles and control mechanisms The drug does not adversely affect the ability to drive vehicles and perform other work that requires increased concentration of attention and speed of psychomotor reactions.
Interaction with other drugs

The drug interaction of the drug Phosphogliv® is not described.
Structure

Structure:
Phospholipids capsul contains: Glycyrrhizic acid 35 mg, Ursodeoxycholic acid 250 mg;

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C. Shelf life is 3 years.